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LSU vs. Duke Women's Basketball Predictions - NCAA Tournament

Duke v South Carolina - 2025 Players Era Tournament

Photo: Ian Maule / Getty Images Sport / Getty Images

A Sweet 16 battle will feature the No. 2 seed LSU Tigers (29-5) and the No. 3 seed Duke Blue Devils (26-8) playing on Friday at Golden 1 Center. The NCAA Tournament matchup tips off at 10 p.m. ET.

LSU is a strong 8.5-point favorite against Duke when the Tigers face off with the Blue Devils on Friday. The point total for the matchup is 145.5.

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LSU vs. Duke Odds and Game Info

  • Game day: Friday, March 27, 2026
  • Game time: 10 p.m. ET
  • TV channel: ESPN
  • Location: Sacramento, California
  • Arena: Golden 1 Center

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LSU vs. Duke Odds and Prediction

  • Spread favorite: LSU (-8.5)
  • Moneyline: LSU (-426), Duke (+330)
  • Total: 145.5 points

Pick ATS:Duke (+8.5)

  • Pick OU: Under (145.5)
  • Prediction: LSU 75, Duke 69

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LSU vs. Duke Comparison

LSU Rank LSU Stat Duke Stat Duke Rank
1st 95.3 Points Scored 74.2 43rd
74th 60.4 Points Allowed 58.7 38th
8th 18.4 Assists 17.4 17th
110th 14.4 Turnovers 14.7 138th
3rd 50.9% Field Goal % 44.0% 64th
4th 34.2% Field Goal % Allowed 37.0% 23rd

LSU Key Players

  • The scoring leader for the Tigers this season is Flau'jae Johnson, who averages 14.3 points, 4.2 rebounds, and 2.6 assists per game.
  • Amiya Joyner is LSU's leading rebounder, grabbing 7.5 per game, while Mikaylah Williams is its best passer, averaging 3.7 assists in each contest.
  • The Tigers get the most three-point shooting production out of Williams, who makes 1.4 threes per game.
  • The LSU leader in both steals and blocks is MiLaysia Fulwiley, who averages 2.9 takeaways and 1.4 rejections per game.

Duke Key Players

  • Toby Fournier averages 17.4 points and 8.0 rebounds per game for the Blue Devils, enough to be the top scorer and rebounder on the squad.
  • Taina Mair's assist statline leads Duke with 5.6 assists per game.
  • Ashlon Jackson averages 2.1 three-pointers per game, the most on the Blue Devils.
  • Duke's leader in steals is Mair (2.4 per game), and its leader in blocks is Fournier (2.2 per game).

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